Human Immunodeficiency Virus (HIV)

FDA Approved Therapies

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

NRTIs block reverse transcriptase, an enzyme HIV needs to make copies of itself.

  • Ziagen® (abacavir)
  • Videx® (didanosine)
  • Emtriva® (emtricitabine)
  • Videx® EC (didanosine)
  • Epivir® (lamivudine)
  • Zerit® (stavudine)
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

NNRTIs bind to and later alter reverse transcriptase, an enzyme HIV needs to make copies of itself.

  • Sustiva® (efavirenz)
  • Intelence® (etravirine)
  • Viramune® (nevirapine)
  • Viramune® XR (nevirapine)
  • Edurant® (rilpivirine)
Protease Inhibitors (PIs)

PIs block HIV protease, an enzyme HIV needs to make copies of itself.

  • Reyataz® (atazanavir)
  • Prezista® (darunavir)
  • Lexiva® (fosamprenavir)
  • Crixivan® (indinavir)
  • Viracept® (nelfinavir)
  • Norvir® (ritonavir)
  • Invirase® (saquinavir)
  • Aptivus® (tipranavir)
Fusion Inhibitors

Fusion inhibitors block HIV from entering the CD4 cells of the immune system.

  • Fuzeon® (enfuvirtide)
Entry Inhibitors

Entry inhibitors block proteins on the CD4 cells that HIV needs to enter the cells.

  • Selzentry® (maraviroc)
Integrase Inhibitors

Integrase inhibitors block HIV integrase, an enzyme HIV needs to make copies of itself.

  • Tivicay® (dolutegravir)
  • Vitekta® (elvitegravir)
  • Isentress® (raltegravir)
Pharmacokinetic Enhancers

Pharmacokinetic enhancers are used in HIV treatment to increase the effectiveness of an HIV medicine included in an HIV regimen.

  • Tybost® (cobicistat)
Combination HIV Medicines

Combination HIV medicines contain two or more HIV medicines from one or more drug classes.

  • Epzicom® (abacavir and lamivudine)
  • Triumeq® (abacavir, dolutegravir, and lamivudine)
  • Trizivir® (abacavir, lamivudine, and zidovudine)
  • Evotaz® (atazanavir and cobicistat)
  • Prezcobix® (darunavir and cobicistat)
  • Atripla® (efavirenz, emtricitabine, and tenofovir disoproxil fumarate)
  • Genvoya® (emtricitabine, rilpivirine, and tenofovir alafenamide)
  • Stribild® (elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate)
  • Odefsey® (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide fumarate)
  • Complera® (emtricitabine, rilpivirine, and tenofovir disoproxil fumarate)
  • Descovy® (emtricitabine and tenofovir alafenamide)
  • Truvada® (emtricitabine and tenofovir disoproxil fumarate)
  • Combivir® (lamivudine and zidovudine)Kaletra® (lopinavir and ritonavir)