PrEP-AP Formulary

PrEP-AP Formulary is the official list of HIV pre-exposure prophylaxis (PrEP) medications that are approved and covered by a specific PrEP Assistance Program (PrEP-AP).

Breaking it down

  • PrEP: Medication taken by HIV-negative people to prevent HIV infection.
  • AP (Assistance Program): A government- or organization-run program that helps cover the cost of PrEP meds and/or related services for eligible individuals.
  • Formulary: The list of drugs the program agrees to pay for.

What the PrEP-AP Formulary typically includes

Depending on the country or region, it usually lists:

  • Approved PrEP medications, such as:
    • Truvada® (emtricitabine/tenofovir disoproxil fumarate)
    • Generic FTC/TDF
    • Descovy® (emtricitabine/tenofovir alafenamide) – often with restrictions
    • In some programs, long-acting injectable PrEP (e.g., cabotegravir) if covered
  • Coverage rules, such as:
    • Who is eligible
    • Prior authorization requirements
    • Clinical criteria (e.g., risk factors, lab results)
  • Pharmacy dispensing requirements
  • Updates or exclusions when drugs are added or removed

Why it matters

  • Determines which PrEP options patients can receive at low or no cost
  • Guides clinicians and pharmacies on prescribing and dispensing
  • Helps patients understand what is covered vs. out-of-pocket

Important note

There is no single universal PrEP-AP formulary. Each program (e.g., U.S. state PrEP-APs, national health services, or insurer-linked programs) maintains its own formulary, which can change over time.